Src相关论文
研究目的原发性肝癌是世界范围内的第二大致死肿瘤,肝细胞肝癌（hepatocellular carcinoma,HCC）约占其中的90%。HCC是一种病情复杂的......
目的 通过网络药理学、分子对接结合体外验证的方法，探究薯蓣皂苷元抗动脉粥样硬化（atherosclerosis,AS）的潜在靶点及作用机制。方法 ......
紧密连接（Tight Junctions,TJs）位于细胞的侧面顶端,发挥“门”和“栅栏”功能。当其结构和功能的完整性遭到破坏时,会引起肿瘤发生......
目的 通过蛋白激酶抑制分析探讨了结肠癌细胞株HT-29与Colo-205增殖的分子机制。方法 选择多种蛋白激酶抑制剂（剂量从0.0006μmol/L......
目的 探讨皮层肌动蛋白(cortactin,CTTN)对食管鳞状细胞癌(简称鳞癌)迁移侵袭的作用及分子机制.方法 在人食管鳞癌细胞系EC109、TE......
该文探讨肿瘤坏死因子α(TNFα)活化信号转导和转录激活因子3(STAT3)的分子机制.采用流式细胞术(FACS)检测TNF受体TNFR1在鼻咽癌细......
先天免疫是抵抗病原微生物侵害的第一道防线。当病毒感染机体后,入侵病毒可通过模式识别受体（PRR）进行识别,病毒RNA主要是双链（ds-）RNA......
目的 通过构建升麻Cimicifugae Rhizoma化学成分-靶点-代谢信号通路网络，探讨其治疗乳腺癌的作用机制。方法利用中药系统药理学数据......
目的:胶质瘤作为临床上最常见的原发性颅脑恶性肿瘤,具有高发病率、高死亡率、高复发率的特点,当前胶质瘤的常规治疗方案是最大安......
背景亚低温（mild hypothermia,32℃-35℃）作为一种临床公认疗法,常用来缓解缺血缺氧引发的神经损伤。亚低温同时也会引发如电解质紊......
目的:通过研究Formin-like2（FMNL2）、Src和Cortactin在60例癌旁正常胃黏膜组织和113例胃腺癌组织中的表达情况,探讨它们之间是否存在......
针对伪装人脸识别问题,基于稀疏表示的分类法(Sparse Representation-based Classification,SRC)的鲁棒性好,分析了SRC 算法及其改......
目的 Src及p-Src的表达与肿瘤的侵袭、转移密切相关，本研究旨在探讨上述粘附分子在骨肉瘤中的表达情况，并对其相互之间关系进行研究，......
Subjects: This study aims to investigate the effect of Src specific siRNA on maintaining bone homeostasis and further il......
Background:TheexpressionofSrcandphospho-Src(p-Src),iscloselyrelatedtotumorinvasionandmetastasis....
Assessment of varied long noncoding RNA and messenger RNA expression levels in adolescent idiopathic
Adolescent idiopathic scoliosis (AIS) is the most common form of spinal deformity, which involves lateral deviation of t......
BACKGROUND:The expression of Src and phospho-Src(p-Src) is closely related to tumor invasion and metastasis. The aim of ......
目的 FHL1 蛋白属于FHL 家族，含有LIM 锌指蛋白结构域.FHL1 在多种肿瘤中表达下调，并抑制肿瘤细胞的生长，长期被认为是一种肿瘤抑制蛋......
目的 EGFRvⅢ 是胶质母细胞瘤中最常见的突变，具有促进胶质母细胞瘤进展的多种活性。本研究旨在通过体内、外实验揭示SRC 家族激酶......
CigarettesmokeextractexposureinducesEGFR-TKIresistanceinEGFR-mutatedNSCLCviamediatingSrc
目的 Thestudyaimstoexplorethemolecularbasisforthepoorresponseofepithelialgrowthfactorreceptortyrosinekinaseinhibitors(EG......
fibronectin upregulation in mesangial cells involves caveolin-1-dependent RhoA-GTP activation via Sr
Background:Increasing evidence indicates that diabetic-mediated renal interstitial fibrosis through extracellular matrix......
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Impaired cell properties and down regulation of FAK-Src complex signaling in autistic B lymphoblasts
Objective Recent studies suggest that one of the major pathways to the pathogenesis of autism is reduced cell migration,......
The saponin DT-13 attenuates tumor necrosis factor-a-induced vascular inflammation associated with S
This study aimed to explore the effect of DT13 (25(R,S)ruscogenin10βdglucopyranosyl(1→2)][βdxylopyranosyl(1→3)]βdfu......
Objective: Receptor of activated C kinase 1(RACK1)is regarded as a scaffolding protein in multiple intracellular signal ......
Zeylenone promotes apoptosis of chronic myelogenous leukemia-derived K562 cells by a mechanism invol
OBJECTIVE The present study was designed to investigate anticancer effect of zeylenone (Zey) on K562 cells derived from ......
Integrin β3 mediated cerebrovascular remodeling through Src/ClC-3 volume regulated Cl- channel signa
Background and Purpose:Cerebrovascular remodeling is one of important risk factors of stroke.The underlying mechanisms a......
IL-6 and p-STAT3 upregulated in tumor-associated macrophages induced by Supernatant of NIH3T3/Src(Y5
The tumor microenvironment could induce macrophages differentiation into Tumor-associated macrophages (TAM),which play a......
GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibit
Available therapeutic options for advanced B cell precursor acute lymphoblastic leukemia(pre-B ALL)are limited.Many lead......
Oxidative stress influences neuronal cell survival and homeostasis,but the mechanisms underlying the biological effects ......
Effects of Low Level Lead Exposure on Brain Barriers: Role of Activation of Nonreceptor Tyrosine Kin
Background Lead (Pb), as a widespread enviromnental pollutant, is known to cause a wide range of neurotoxic effects, inc......
Aim: Our previous work demonstrated that extracellular signal-regulated kinase 1/2 (ERK1/2) pathway regulates autophagic......
Inhibition of Nonsmall Cell Lung Cancer Cell Migration by Protein Arginine Methyltransferase 1-small
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On September 10， the Chi- na-ASEAN Business Leaders Forum and a Special Meeting on the 30th Anniversary of China-ASEAN Di......
According to EVsales， a total of 3，124，800 new energy vehicles （NEVs） were sold worldwide in 2020， marking a year-on-year incr......
